Gyre Therapeutics Inc
GYRE
ISIN US4037831033 / Valor 130270397
Gyre Therapeutics Inc
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About company
Gyre Therapeutics Inc, based in San Diego, CA, is a biopharmaceutical entity engaged in the development and commercialization of innovative treatments for chronic liver diseases, with a primary focus on Metabolic Dysfunction Associated Steatohepatitis (MASH-associated liver fibrosis, formerly known as Nonalcoholic Steatohepatitis or NASH) in the United States. The company's flagship product, Hydronidone (F351), is under investigation in the U.S. for its efficacy in treating liver fibrosis across a spectrum of chronic liver conditions, supported by an active Investigational New Drug (IND) application. This application is bolstered by a comprehensive nonclinical program compliant with Good Laboratory Practice (GLP) and Phase 1 clinical trial data on the pharmacokinetics, safety, and tolerability of Hydronidone. The decision to target the MASH indication in the U.S. is informed by promising results from mechanistic studies in MASH rodent models and a Phase 2 clinical study in China for chronic Hepatitis-B induced liver fibrosis, which demonstrated safety and efficacy. Furthermore, Gyre is expanding its portfolio in China through Beijing Continent, a subsidiary with a controlling interest, advancing a diverse pipeline that includes pirfenidone—an approved treatment for Idiopathic Pulmonary Fibrosis in China—among other investigational drugs for various conditions.
Summarized from source with an LLMView SourceSector: HealthcareKey figures
Performance
Volatility
1757 M
Market cap (USD)
35,807
Daily traded volume (Shares)
12.87 / 11.72
1 day high/low (USD)
52 weeks high/low (USD)
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